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Continuous variables are presented as mean and 95% confidence interval, and categorical variables are represented as frequencies and percentages. Statistical analysis was performed using IBM SPSS Statistics 27.0.

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Cardiac magnetic resonance (CMR) was performed at the discretion of the treating cardiologist. All patients were scheduled within the 2 following business days and underwent standardized cardiologic assessment including electrocardiography (ECG), echocardiography, and determination of NT-proBNP and high-sensitive troponin T. Since then, we noted increasing requests from General Practitioners for urgent cardiologic consultation of patients with suspected myocarditis after COVID-19 vaccination.

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On May 7th 2021, the European Medicines Agency (EMA) announced an official investigation of case reports of myopericarditis in temporal relation to COVID-19 vaccination, which was updated on June 11th. In Germany, vaccination against coronavirus disease 2019 (COVID-19) was approved on December 21st 2020 and the first patient treated on December 26th.











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